Chemical and Biological Mass Spectrometer
(CBMS-Block II)
The Chemical Biological
Mass Spectrometer (CBMS) is
an ion trap mass spectrometer that is capable of biological
agent detection when connected to an aerosol collector/concentrator
and of chemical detection when connected to a chemical
probe. Agents are detected through an algorithm which contains
the profiles of threat agents. The system’s ability
to operate in both the MS and MS/MS modes allows it to
screen out battlefield interferents. The system is controlled
by a touch screen computer
Battlefields do not mimic pristine
lab conditions, a point amply demonstrated during the Gulf War
when, some experts believe, instruments designed to detect biological
weapons proved unreliable. Engine exhaust, exhaust from weapons,
spilled fuel, lubricants, and smoke all acted as background distractions,
making it difficult for the instruments to distinguish a potentially
deadly biological agent from non-lethal bacteria and chemicals.
Now, ORNL has remedied the problem with the CBMS.
The unit, now in prototype and set to enter production in 2001,
was engineered at the behest of the U.S. Army’s Soldier
and Biological Chemical Command, and designed (both inside and
out) for real world battlefield conditions. About the size of
a desktop computer, the rugged system will be capable of detecting
a very wide range of lethal chemical and biological weapons,
including bacteria, toxins and viruses, as well as such hazardous
chemical agents as nerve gas and blister agents.
The unit works by collecting an air sample, classifying
it according to size, then heating it to break down its molecules.
The sample is then moved into an ion trap mass spectrometer,
where its mass-to-charge ratio and its chemical signature are
compared against an extensive onboard library of known toxic
agents, such as anthrax and VX gas.
The folks at Oak Ridge and the Department
of Defense see applications for the new device in the private
sector as well. With just a few minor modifications, it could
be used to test processed food and in industrial safety and
health care applications.
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